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. Author manuscript; available in PMC: 2021 Feb 5.
Published in final edited form as: Biochem Biophys Res Commun. 2019 Nov 21;522(2):415–421. doi: 10.1016/j.bbrc.2019.11.110

Fig. 3. Inhibition of ESCRT-III promotes ferroptosis.

Fig. 3.

(A) Western blot analysis of CHMP5 and CHMP6 expression in indicated gene knockdown PANC1 or HepG2 cells. (B-E) Analysis of cell death (B), intracellular MDA (C), intracellular iron (D), and HMGB1 release (E) in indicated PANC1 or HepG2 cells in response to erastin (10 μM) or RSL3 (0.5 μM) for 12 h (n = 3, *P < 0.05).