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. 2019 Aug 22;9(2):195–218. doi: 10.1016/j.jcmgh.2019.08.004

Figure 5.

Figure 5

CD38+PD1+CD8+T cells are enriched in TILs. (A) tSNE map of CD8+ T cells in TILs (yellow dots), NTILs (purple dots), and PBMCs (green dots). (B) tSNE maps showing the expression level and the distribution of each indicated marker. The color scale indicates the relative expression levels. (C) tSNE map with each cluster of CD8+ T cells colored differently. (D) Box plots showing the frequency of CD8+ T cells in each cluster significantly enriched in TILs. (E) Heatmap showing the normalized expression of the markers for the indicated clusters. The color scale indicates the relative expression levels. *P ≤ .05, Wilcoxon signed-rank test, adjusted with the Benjamini and Hochberg method. ns, not significant.