Table 1.
GEO-derived regulatory factors of OCIAD1.
| Regulators in GEO | Reported change in AD | Effects on OD1 |
|---|---|---|
| STAT3, p53, Myb, CD133, CXCL4/PF4, APP, SRF, Homocystein, d-serine | Elevated | Upregulation |
| CTNNB1, Notch, CREB, IRS3, IRS4, IRS1, DHT, VitE | Decreased | Suppressor |
| Estradiol, HDACs, Aging | Uncertain | Uncertain |
Note: Upregulators: STAT3, signal transducer and activator of transcription3; p53, tumor protein p53; Myb, v-myb avian myeloblastosis viral oncogene homolog; CD133, prominin 1; CXCL4/PF4,C-X-C motif chemokine 4; APP, amyloid protein precursor; and SRF, serum response factor. Downregulators: CTNNB1, β-catenin; CREB, cAMP responsive element binding protein; IRS1/3/4, insulin receptor substrate 1; and DHT, dihydrotestosterone. Uncertain: HDACs, Histone deacetylases.