Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jan 8;13:173–183. doi: 10.2147/OTT.S240113

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Zhang et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

FOXP1 was a target of miR-345-5p. (A) The binding sites of miR-345-5p and FOXP1 3ʹUTR were displayed. (B, C) Dual-luciferase reporter assay was performed to confirm the relationship between miR-345-5p and FOXP1. (D) FOXP1 expression was tested in HCC tissues and adjacent normal tissues. (E) Spearman correlation curve depicted a negative correlation between miR-345-5p and FOXP1 levels in HCC tissues. (F) The level of FOXP1 was measured in THLE-2 cells and HCC cell lines (Huh-7 and SK-HEP-1). (G–J) The mRNA and protein levels of FOXP1 were detected in Huh-7 and SK-HEP-1 cells introduced with miR-NC, miR-345-5p, anti-miR-NC or anti-miR-345-5p by qRT-PCR and Western blot assay. *P < 0.05.