Figure 1.

Reduced abdominal aortic aneurysm (AAA) formation in Gadd153-/-mice. A, B. Aortic diameters in both Gadd153-/-mice and WT mice were measured preperfusion, immediately postperfusion, and at 7 and 14 days post perfusion. C. Changes in mean blood pressure (MBP) in AngII-infused Gadd153-/-mice (Red) and WT mice (WT). The MBP was monitored by an intracarotid-telemetry method continuously for 14 days. Data are mean ± SEM. P < 0.05 is considered statistically significant, #indicates compared to WT mice.