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Matrix metalloproteinase (MMP) expression is attenuated in the aortas of Gadd153-/-mice. Quantitative polymerase chain reaction (PCR) analysis of MMP2 mRNA expression in the abdominal aortas of Gadd153-deficient mice at A. 14 days after angiotensin II (AngII) infusion. B. Representative images of Verhoeff-van Geison-stained abdominal aortic sections from Ang II-treated Gadd153-/-mice. Arrow indicates breakage in the elastin layer.
