Table 1.
Baseline Characteristics of the Study Participants
| Anorexia nervosa (n = 11) | |
|---|---|
| Age (years) | 37.2 ± 2.3 |
| BMI (kg/m2) | 17.8 ± 0.5 |
| % of ideal body weight | 76.2 ± 2.1 |
| Number of years since onset of anorexia nervosa | 16 [10, 23] |
| Duration of amenorrhea (months) | 157 [36, 180] |
| History of stress fracture | 27% (n = 3) |
| History of any prior fracture (stress or traumatic) | 45% (n = 5) |
| % self‐reporting at least 10 hours/week of physical activity or running more than 10 miles per week | 55% (n = 6) |
| 25‐OH vitamin D (ng/mL) | 38.2 ± 5.1 |
| IGF‐I (ng/mL) | 150 [140, 160] |
| P1NP (ng/mL) | 49.5 [35.9, 71.1] |
| Osteocalcin (ng/mL) | 11.7 [7.2, 31.4] |
| CTX (ng/mL) | 0.51 ± 0.09 |
| Sclerostin (pg/mL) | 91.7 ± 4.8 |
| BMD | |
| Lumbar spine (L1–L4) (g/cm2) | 0.78 ± 0.03 |
| Lumbar spine T‐score | −2.47 ± 0.28 |
| Lumbar spine Z‐score | −2.24 ± 0.30 |
| Lateral spine (L2–L4) (g/cm2) | 0.60 ± 0.03 |
| Lateral spine T‐score | −2.59 ± 0.33 |
| Lateral spine Z‐score | −1.96 ± 0.30 |
| Total hip (g/cm2) | 0.74 ± 0.03 |
| Total hip T‐score | −1.69 ± 0.24 |
| Total hip Z‐score | −1.52 ± 0.23 |
| Femoral neck (g/cm2) | 0.64 ± 0.02 |
| Femoral neck T‐score | −1.89 ± 0.20 |
| Femoral neck Z‐score | −1.62 ± 0.20 |
| Bone marrow adipose tissue | |
| L4 vertebra (lipid/water) | 1.05 ± 0.12 |
| Femoral metaphysis (lipid/water) | 5.47 [3.44, 7.87] |
| Femoral diaphysis (lipid/water) | 7.28 ± 0.73 |
| Femoral epiphysis (lipid/water) | 7.43 ± 0.79 |
We report (mean ± SEM) or median [interquartile range] when data were not normally distributed.