Table 2.
Expression of E-cadherin, β-catentin, N-cadherin and Vimentin proteins in patients with CIN and cervical cancer
| Normal cervical epithelia (N=66) | CINII-III (N=46) | CSCC (N=109) | P | |
|---|---|---|---|---|
| β-catentin expression Mean (SD) | 0.411 (0.0493) | 0.211 (0.0393) | 0.163 (0.0191) | 0.023 |
| E-cadherin expression Mean (SD) | 0.409 (0.0472) | 0.301 (0.0376) | 0.198 (0.0385) | 0.009 |
| N-cadherin expression Mean (SD) | 0.201 (0.0403) | 0.297 (0.0487) | 0.497 (0.0665) | 0.032 |
| Vimentin expression Mean (SD) | 0. 203 (0.0390) | 0.313 (0.0398) | 0.499 (0.0671) | 0.008 |
(r=0.421, P=0.009; r=0.650, P=0.005), and a negative correlation of Pin1 expression with E-cadherin and β-catentin expression (r=-2.98, P=0.037; r=-3.09, P=0.029), respectively.