Apoptotic rates were detected by flow cytometry after siRNA treatment in HGC27 cells. UL, necrotic cells; UR, terminal apoptotic cells; LR, early apoptotic cells. Compared with NC, *P < 0.05. Compared with siCXCL1 or siCXCL8, #P < 0.05. Experiments were performed in triplicate. Data represent the mean ± S.D. from three independent experiments.