Table 2.
Top 5 enriched biological processes for upregulated genes induced by corticosterone treatment
| GO Term ~ Biological Process | Genes | N (%) | P-Value |
|---|---|---|---|
| GO:0071549 Cellular response to dexamethasone stimulus | ICAM1, ASS1, SERPINF1, ABCB1B, SERPINE1, FOXO1, BCL2L1, TRIM63, AQP1, ASL, ERRFI1, DDIT4 | 12 (1.9) | 3.02E-06 |
| GO:0045766 Positive regulation of angiogenesis | PRKCA, HYAL1, RAMP2, LGALS3, C3, PGF, AQP1, PTGIS, ADM, HIPK2, SERPINE1, RHOB, ZC3H12A, RRAS, THBS1, CTSH | 16 (2.5) | 6.97E-06 |
| GO:0001666 Response to hypoxia | CAV1, ALAD, AHCY, PGF, ALDOC, BCL2L1, CITED2, PTGIS, KDM3A, LIMD1, PAK1, ICAM1, RAMP2, CYP1A1, CRYAB, VHL, CST3, UBE2B, PRKCD, DDIT4, ITPR2, PENK, ADM, ABCB1B, PSEN2 | 25 (3.9) | 1.10E-05 |
| GO:0042594 Response to starvation | ZFP36, ADSSL1, SORBS1, ADM, ULK1, SERPINE1, NUCB2, PDK4, AK3, FSTL1 | 10 (1.6) | 5.24E-05 |
| GO:0051384 Response to glucocorticoid | CXCL1, BCKDHA, CAV1, ALAD, ASS1, C3, IL6R, TRIM63, CTSL, DUSP1, ADM, S100B, SULT1A1, LCAT, PIK3R1 | 15 (2.4) | 1.27E-04 |