Table 3.
Results of univariate analyses of overall survival (OS) time
| Variables | n | Mean OS (months) | Log-rank | P value |
|---|---|---|---|---|
| VM | 128.741 | <0.001 | ||
| Negative | 117 | 71.0±13.5 | ||
| Positive | 69 | 40.6±17.1 | ||
| ALDH1 | 106.036 | <0.001 | ||
| Negative | 79 | 76.0±11.4 | ||
| Positive | 107 | 47.6±17.9 | ||
| Beclin1 | 52.807 | <0.001 | ||
| Negative | 77 | 73.4±14.5 | ||
| Positive | 109 | 50.0±19.3 | ||
| p16 | 53.718 | <0.001 | ||
| Negative | 130 | 52.9±19.4 | ||
| Positive | 56 | 75.6±14.9 | ||
| Age (year) | 0.192 | 0.661 | ||
| <60 | 76 | 59.9±21.3 | ||
| ≥60 | 110 | 59.6±20.7 | ||
| Gender | 0.095 | 0.758 | ||
| Male | 104 | 58.1±21.6 | ||
| Female | 82 | 61.8±20.1 | ||
| Smoking | 0.063 | 0.802 | ||
| No | 75 | 59.4±21.7 | ||
| Yes | 111 | 59.9±20.5 | ||
| Alcohol | 0.753 | 0.386 | ||
| No | 66 | 59.7±22.3 | ||
| Yes | 120 | 59.7±20.2 | ||
| Location | 8.966 | 0.110 | ||
| Tongue | 70 | 65.1±19.5 | ||
| Gingiva | 36 | 53.0±20.5 | ||
| Oral floor | 28 | 61.2±22.4 | ||
| Jaw | 25 | 56.8±18.9 | ||
| Buccal mucosa | 15 | 57.2±21.9 | ||
| Others | 12 | 53.8±24.5 | ||
| Grade | 97.222 | <0.001 | ||
| Well | 84 | 70.7±15.1 | ||
| Moderate | 74 | 57.5±17.2 | ||
| Poor | 28 | 32.5±18.5 | ||
| Primary tumor | 369.471 | <0.001 | ||
| T1 | 90 | 74.1±13.0 | ||
| T2 | 56 | 56.1±11.5 | ||
| T3 | 26 | 40.2±12.3 | ||
| T4a | 14 | 17.6±6.5 | ||
| LNM | 383.472 | <0.001 | ||
| N0 | 135 | 69.5±13.6 | ||
| N1 | 37 | 40.2±10.0 | ||
| N2 | 14 | 17.3±5.8 | ||
| TNM stage | 434.913 | <0.001 | ||
| I | 82 | 77.1±9.1 | ||
| II | 48 | 59.4±9.1 | ||
| III | 39 | 41.2±8.7 | ||
| IVA | 17 | 18.8±6.8 |