Figure 2.

Overexpression of microRNA-128 increases radio-sensitivity by increasing cellular senescence in U87 glioma cells. A: Cell growth curve of U87 cells exposed to 2 and 8 Gy X-ray radiation after treatment with negative control or miR-128 as above. Values represent mean ± standard deviation (SD) for three wells. *mean p value ≤0.05, all compared with negative control. B: Following 72 h of exposure to X-ray radiation at 2 and 8 Gy doses, the U87 glioma cells were treated by SA-β-Gal staining and images were captured under phase-contrast microscopy. C: Under the microscope the SA-β-Gal positive cells were counted and the quantitative results are presented as the mean ± standard deviation of three independent experiments. *P<0.05 vs. control. **P<0.05 comparison among groups.