miR-26b regulates host immune response towards M.tb through targeting TAK1. THP-1 cells were transfected with miR-26b mimics, pcDNA-TAK1, or both. 24 hr after transfection, cells were infected with H37Rv at MOI 10. 24 hr post-infection, supernatant were harvested for ELISA assay to detect IFN-γ (A), IL-1β (B), IL-6 (C) and TNF-α (D) secretion. All data represent the mean value ± SD of at least three independent experiments. *P < 0.05, **P < 0.01 vs non-transfected groups; ##P < 0.01 vs miR-26b-transfected groups.