The associations of 12 DEMs with TNSS score. The expressions of miR-126-5p (B), miR-19a-5p (H) and miR-181c-3p (K) were positively correlated with TNSS score; while the correlations between another 9 DEMs (miR-1908-5p (A), miR-92a-3p (C), miR-572 (D), miR-1228-3p (E), miR-483-5p (F), miR-125a-5p (G), miR-26a-5p (I), miR-106a-5p (J) and miR-3177-3p (L)) and TNSS were not found. The association between 12 validated miRNAs and TNSS score was analyzed by Spearman test. P < 0.05 was considered statistically significant.