The expression level of miR-182 affected cell growth of A375 cells. A. The expression level of miR-182 was detected by qRT-PCR by transfection of miR-182 mimics and inhibitors, ***P<0.001, ###P<0.001. B. Wound Healing assay was used to detect the ability of cell migration, **P<0.01, #P<0.05. C. CCK-8 assay was used to detect cell proliferation by transfecting with mimics-nc, inhibitors-nc, miR-182 mimics, and inhibitors in A375 cells. ***P<0.001, ##P<0.01. D. Transwell assay was used to detect cell invasion, ***P<0.001, ###P<0.001.