Overexpression of miR-182 and knockdown of APC affect growth of melanoma cells. A. mRNA expression of APC was detected by PCR, ***P<0.001. B. Protein expression of APC was detected by WB, ***P<0.001. C. Cell viability was detected at overexpression of miR-182 and knockdown of APC, **P<0.01, #P<0.05. D. Cell apoptosis was detected at overexpression of miR-182 and knockdown of APC, ***P<0.001, ##P<0.01. E. Protein expression of β-catenin was detected by immunofluorescence assay at overexpression of miR-182 and knockdown of APC, ***P<0.001, ##P<0.01.