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. 2018 May 1;11(5):2522–2529.

Figure 5.

Figure 5

TPT1 down-regulation suppresses cell proliferation and induces cell cycle arrest in colorectal cancer cell lines. A. Expression of TPT1 in HCT116 and SW480 cell lines with si-TPT1 and si-con transfection. B. Cell proliferation was measured by CCK-8 assay and C. Cell cycle was measured by flow cytometry in HCT116 and SW480 cell lines with control or miR-455-3p inhibitor or miR-455-3p inhibitor and si-TPT1 transfection. (**P < 0.01, *P < 0.05, ns not significant) miR-455-3p: microRNA-455-3p; TPT1: The tumor protein translationally controlled 1; CCK-8: cell counting kit-8; si-TPT1: siRNA targeting TPT1; si-con: control siRNA.