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. 2018 May 1;11(5):2408–2418.

Figure 4.

Figure 4

Correlation of frequency of TIGIT-expressing natural killer (NK) cells with disease activity and severity of SLE. A. The frequency of TIGIT-expressing NK cells in systemic lupus erythematosus (SLE) patients was significantly decreased in active SLE patients compared to inactive SLE patients. B. The frequency of TIGIT-expressing NK cells in SLE patients correlated negatively with SLE disease activity index (SLEADI). C. The frequency of TIGIT-expressing NK cells in SLE patients was significantly increased after treatment. D. The frequency of TIGIT-expressing NK cells was significantly decreased in patients with positive anti ribosomal RNP (anti-rRNP) compared to patients with negative anti-rRNP. E. The frequency of TIGIT-expressing NK cells was significantly decreased in SLE patients with decreased complement 3 (C3). F. The frequency of TIGIT-expressing NK cells was significantly decreased in SLE patients with decreased complement 4 (C4).