Upregulation of STIM1 can induce podocyte apoptosis. A, B. Cellular apoptosis and the apoptosis rate were detected using flow cytometry in the different treatment groups. C. The expressions of Beclin-1, Bcl-2, and Caspase-3 proteins were standardized using β-actin. D-F. Western blotting was performed to detect the expression levels of Beclin-1, Bcl-2, and Caspase-3 proteins in MPC5 cells cultured in different sera. (**P<0.01).