Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Oct 30;7(4):36. doi: 10.3390/proteomes7040036

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Comparison of methods to study proteoforms. 2DE is a top-down analysis. MS/MS analysis after enzymatic digestion is a “selective” bottom-up analysis. 2DE—two-dimensional gel electrophoresis, MDLC—multiple dimensional liquid chromatography, MS—mass spectrometry, MS/MS—tandem mass spectrometry, PTM—post-translational modification, LC—liquid chromatography, PMF—peptide mass fingerprint. Modified from Zhan X. et al. [70] with permission from Elsevier publisher open access publication, copyright 2018.