Table 1.

Identity and extent of inhibition of compounds identified as “hits” during primary screenings of the Pathogen Box^® in search for compounds with inhibitory activity against C. auris strain 0390 under planktonic and biofilm growing conditions.

Hit Compounds Inhibition of Planktonic Growth	% Inhibition of Planktonic Growth at 5 µM	% Inhibition of Planktonic Growth at 20 µM	Hit Compounds Inhibition of Biofilm Formation	% Inhibition of Biofilm Formation at 5 µM	% Inhibition of Biofilm Formation at 20 µM
Amphotericin B	93	89	Amphotericin B	97	99
Posaconazole	95	86	Posaconazole	72	78
Miltefosine	n/a	102	Miltefosine	n/a	98
Iodoquinol	86	98	Iodoquinol	n/a	n/a
MMV676162	n/a	65	MMV676162	n/a	n/a
Pentamidine	n/a	84	Pentamidine	61	n/a
MMV102872	n/a	88	MMV102872	n/a	n/a
MMV688852	n/a	70	MMV688852	n/a	n/a
MMV687775	n/a	61	MMV687775	n/a	n/a
MMV688417	n/a	60	MMV688417	n/a	n/a
MMV659010	62	n/a	MMV659010	n/a	n/a
MMV688938	n/a	62	MMV688938	n/a	n/a

n/a indicates the inhibitory values below the target value of 60% inhibition.