Figure 1.

Timeline of technological advances to study RNA-Protein and RNA-Chromatin interactions. Upper panel (light sea-green box) depicts in chronological order the prominent methods (in blue) to detect RNA interactions with chromatin. Examples of some of the functionally validated lncRNAs from each of these studies are shown (in black) below the corresponding method. Middle panel depicts the year in which these methodologies were published. Lower panel (light pink box) likewise shows in chronological order methods (in green) to identify RNA interactions with proteins.