Table 2.
Baseline clinical profile of the patients registered in a comprehensive sickle cell disease program led by an NGO in a tribal area of Gujarat, India during December 2015–June 2017; N = 404.
| Characteristics | Categories | Children, N = 105 | Adults, N = 299 | Total | |||
|---|---|---|---|---|---|---|---|
| n | (%) | n | (%) | n | (%) | ||
| Hospitalized at registration | Yes | 81 | (77.1) | 210 | (70.2) | 113 | (28.0) |
| No | 24 | (22.9) | 89 | (28.8) | 291 | (72.0) | |
| Number of pain crisis episodes in the last year | 0 | 23 | (21.9) | 25 | (8.4) | 48 | (11.9) |
| 1 | 21 | (20.0) | 42 | (14.0) | 63 | (15.6) | |
| 2 | 20 | (19.1) | 72 | (24.1) | 92 | (22.8) | |
| >=3 | 41 | (39.0) | 160 | (53.5) | 201 | (49.8) | |
| Number of hospitalizations in the last year | 0 | 76 | (72.4) | 197 | (65.9) | 273 | (67.6) |
| 1 | 18 | (17.1) | 66 | (22.1) | 84 | (20.8) | |
| 2 | 6 | (5.7) | 22 | (7.3) | 28 | (6.9) | |
| >=3 | 5 | (4.8) | 14 | (4.7) | 19 | (4.7) | |
| Number of blood transfusions in the last year | 0 | 89 | (84.7) | 243 | (81.3) | 332 | (82.2) |
| 1 | 9 | (8.6) | 30 | (10.0) | 39 | (9.7) | |
| >=2 | 7 | (6.7) | 26 | (8.7) | 33 | (8.2) | |
| Severe anemia | Yes | 24 | (22.9) | 37 | (12.4) | 61 | (15.1) |
| No | 81 | (87.1) | 262 | (87.6) | 343 | (84.9) | |
| Presence of sickle cell complications | Yes | 1 | (1.0) | 15 | (5.0) | 16 | (4.0) |
| No | 104 | (99.0) | 284 | (95.0) | 388 | (96.0) | |
| Genotype | HBS *- homozygous | 57 | (54.3) | 138 | (46.2) | 195 | (48.3) |
| HBS *- B-thalassaemia |
2 | (1.9) | 4 | (1.34) | 6 | (1.5) | |
| Not Available | 46 | (43.8) | 157 | (52.5) | 203 | (50.2) | |
* Sickle hemoglobin.