Table 1.

The Toronto and the SWEP53 protocol for children

The Toronto protocol (2011) children	Adrenocortical carcinoma	Brain tumor	Soft tissue and bone sarcoma	Leukaemia or lymphoma
	Ultrasound of abdomen and pelvis every 3–4 months	Annual brain MRI	Annual rapid total body MRI	Blood test every 4 months: complete blood count, erythrocyte sedimentation rate, lactate dehydrogenase
	Complete urinalysis every 3–4 months
	Blood tests every 4 months: β-human chorionic gonadotropin, alpha-fetoprotein, 17-OH-progesterone, testosterone, dehydroepiandrosterone sulfate, and rostenedione
The SWEP53 Protocol children	Ultrasound of abdomen and pelvis every 3–4 months Complete urinalysis every 3–4 months	None unless suspicion raised at the clinical check-up performed every 3 months	None unless suspicion raised at the clinical check-up performed every 3 months	None unless suspicion raised at the clinical check-up performed every 3 months