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. 2020 Jan 13;21:14. doi: 10.1186/s12882-020-1685-3

Table 1.

Baseline characteristics of patients who underwent kidney biopsy and their baseline eosinophilia on hematology

Demographics No Eosinophilia
≤ 4%
(n = 113)
Peripheral Eosinophilia
>  4%
(n = 65)
P-value
Female 56 (50%) 21 (32%) 0.025
Age, mean (SD), y 51 (17) 53 (18) 0.51
Race
 White 57 (50%) 31 (48%) 0.55
 Black 47 (42%) 30 (46%)
 Other 9 (8%) 4 (6%)
Asthma 17 (15%) 8 (12%) 0.61
Filarial Disease 0 (0%) 1 (2%) 0.19
HIV 15 (14%) 4 (6%) 0.13
Transplant 18 (16%) 8 (13%) 0.54
HTN 80 (71%) 42 (70%) 0.84
Baseline eGFR stagea
 I 63 (56) 49 (76) 0.013
 II 35 (31) 9 (13)
 III 10 (8) 3 (5)
 IV 1 (1) 3 (5)
 early V 4 (4) 1 (1)
Diabetes 19 (17) 15 (23) 0.32
Mean UPCR (SD), g 3.4 (9.9) 3.2 (4.5) 0.86
Mean serum Cr at biopsy (SD), mg/dl 2.9 (2.9) 3.9 (3.9) 0.043
Indication for kidney biopsy
 AKI 45 (40) 23 (37) 0.03
 CKD 5 (4) 0 (0)
 AKOCKD 39 (27) 35 (53)
 Nephrotic Syndrome 24 (21) 7 (10)

Results expressed as n (%), unless otherwise indicated

abased on eGFR by CKD-Epi equation

Abbreviations: HIV human immunodeficiency virus; HTN hypertension; eGFR estimated glomerular filtration rate; UPCR urine-protein-creatinine-ratio; Cr creatinine; AKI acute kidney injury; CKD chronic kidney disease; AOCKD acute on chronic kidney injury