Fig. 2.

Effect of oral NAC administration on L. amazonensis infected mice on mechanical and thermal hyperalgesia. Mechanical (A) and thermal hyperalgesia (B) were assessed at the time points indicated after subcutaneous infection of L. amazonensis into the mice hind paw. NAC administration (20 mg/kg) produced significant improvements in both scores. Values are means ± SEM ^#P < 0.05, ^##P < 0.01, and ^###P < 0.001 vs. L. amazonensis infected mice