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BUSP-induced OF behavior in B6 mice. Effects of BUSP (0–10 mg/kg) in B6 males (n = 20 for saline and 1 mg/kg and n = 10 for all other doses) on (A) percent of time spent in the center of the open field, (B) distance traveled in 10 min, and (C) number of rearings. Control group mean is indicated by a horizontal dashed line. Significance compared to vehicle is shown as *p < 0.05, **p < 0.01, ***p < 0.001.
