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mCPP-induced OF behavior in B6 mice. Effects of mCPP (0–2 mg/kg) in B6 males (n = 10 and n = 15 for saline and mCPP doses, respectively) on (A) percent of time spent in the center of the open field, (B) distance traveled in 10 min, and (C) number of rearings. Data are presented as mean ± SEM. Control group mean is indicated by a horizontal dashed line. Significance compared to vehicle is shown as *p < 0.05, **p < 0.01, ***p < 0.001.
