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Key dates and relevant protection periods for sofosbuvir, imatinib, and trastuzumab, based on SPCs granted in France [56, 64, 71]
| Product | Sofosbuvir | Imatinib | Trastuzumab |
|---|---|---|---|
| Year of market launch | 2013 | 2001 | 1999 |
| Year sales revenue surpassed R&D investment | 2015 | 2003 | 2000 |
| Basic patent expiry date | 26/03/2028 | 25/03/2013 | 15/06/2012 |
| SPC term | > 9 months | > 3 years 8 months | > 2 years 1 month |
| SPC expiry date | 17/01/2029 | 21/12/2016 | 29/07/2014 |
