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. 2020 Jan 13;20:17. doi: 10.1186/s12883-019-1586-x

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© The Author(s). 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Brain MRI of the patient at different ages. Axial and coronal T2-weighted images. Supratentorial progressive cortical and subcortical atrophy with ex vacuo ventriculomegaly and diffuse deep white matter hyperintensities. Note that MRI is already abnormal at 5yo, before onset of regression. Cerebellar atrophy is only marginal. Basal ganglia, U-fibres, optic radiations, internal capsule and hippocampi were globally preserved