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. 2020 Jan 13;39:12. doi: 10.1186/s13046-020-1522-3

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© The Author(s). 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — KDM4B is frequently up-regulated in colorectal tumor tissues and positive expression is correlated with an unfavorable prognosis. a and b Representative results of immunohistochemical staining for KDM4B expression in colorectal cancer tissues (a) and adjacent nontumor tissues (b). c Dot plots showing immunohistochemical scores and mean ± SD of KDM4B in colorectal tumor and NT tissues. d Kaplan-Meier survival curves of patients with colorectal cancer in the tissue microarray (n = 80) segregate into high- and low-KDM4B expression groups. e Kaplan-Meier survival curves of patients with colorectal cancer in TCGA database segregate into high- and low-KDM4B expression groups