Table 2.
Univariable and multivariable analyses of overall survival (OS) and clinicopathologic variables in 100 cases of colon cancer
| Variable | No. | HR (95% CI) | p value | HR (95% CI) | p value |
|---|---|---|---|---|---|
| Gender | |||||
| Male | 59 | 1.262 (0.721–2.207) | 0.415 | NA | |
| Female | 41 | ||||
| Age | |||||
| < 60 | 24 | 1.449 (0.727–2.889) | 0.292 | NA | |
| ≥ 60 | 76 | ||||
| Tumor size(cm) | |||||
| < 5 | 34 | 1.43 (0.801–2.554) | 0.226 | NA | |
| ≥ 5 | 66 | ||||
| T-stage | |||||
| 1/2 | 3 | 1.262 (0.761–2.092) | 0.367 | NA | |
| 3/4 | 97 | ||||
| N-stage | |||||
| N0 | 53 | 1.819 (1.219–2.712) | 0.003 | 2.438 (1.258–4.724) | 0.008 |
| N1 | 35 | ||||
| N2 | 12 | ||||
| M-stage | |||||
| M0 | 95 | 5.142 (1.984–13.326) | 0.001 | 9.299 (2.143–40.355) | 0.003 |
| M1 | 5 | ||||
| Clinical Stage | |||||
| I/II | 52 | 1.893 (1.206–2.973) | 0.006 | 0.568 (0.249–1.297) | 0.179 |
| III/IV | 48 | ||||
| KDM4B expression | |||||
| Low | 33 | 2.025 (1.062–3.863) | 0.032 | 1.862 (0.964–3.597) | |
| High | 67 | 0.044 | |||