Fig. 4.

Global view of temporal circRNA expression profiles in mice brain during T. gondii infection. a Statistics of differentially expressed circRNA among samples. b Venn diagram representation of differentially expressed circRNA sharing and exclusive constitutively presented among different time points vs. Control sample. c Hierarchical clustering of circRNA expression data. Unsupervised hierarchical clustering was performed using Pearson′s correlation as distance measure and Average-linkage for linkage analysis. Brown and blue indicate higher and lower abundance, respectively. Sample groups including acutely infected, chronically infected and control are labeled as AI, CI, and Con, respectively