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. 2020 Jan 13;20:20. doi: 10.1186/s12935-020-1101-x

Table 1.

Association of EPHA5 expression with clinicopathological features in ESCC patients

Characteristic Patients with FFPE EPHA5 expression χ2 P valuea
Tissue (n = 48) Negative + low High
Age 0.844 0.358
 ≤ 65 23 20 3
 > 65 25 18 7
Sex 0 1
 Male 34 27 7
 Female 14 11 3
Histologic grade 0.448 0.503
 Grade I–II 37 28 9
 Grade III 11 10 1
TNM stage 0.034 0.854
 I-II 18 15 3
 III-IVA 30 23 7
Lymph node status 3.158 0.076
 Negative 24 22 2
 Positive 24 16 8
Vascular or nerve invasion 0 1
 Negative 34 27 7
 Positive 14 11 3

Lymph node status: negative, no positive nodal metastases; positive, number of positive nodal metastases ≥ 1

FFPE, formalin fixed paraffin-embedded

aPearson’s χ2 test