Table 2.
IHC expression analysis on patients with prostate cancer CNS metastases
| Case No. |
Site | ERG (+/−) | PTEN (+/−) | CHD1 (H-score) | MAP3K7 (H-score) |
|---|---|---|---|---|---|
| 1 | C6-T1 (Dural) | Neg | N/A | 212 | 90 |
| 2 | Cerebellum (Dural) | Neg | Pos | 106 | 80 |
| 3 | Frontal Lobe (Dural) | Neg | Pos | 110 | 181 |
| 4 | Parieto-occipital (Dural) | Neg | Pos | 224 | 79 |
| 5 | L4 (Dural) | Neg | N/A | 229 | 107 |
| 6 | Cerebellum (Dural) | Neg | Pos | 181 | 97 |
| 7 | T-spine (Dural) | Neg | Pos | 190 | 83 |
| 8 | C7 (Dural) | Neg | Neg | 233 | 194 |
| 9 | Occipital (Parenchymal) | Neg | Neg | 101 | 69 |
| 10 | Thalamus (Parenchymal) | Pos | Neg | 277 | 86 |
| 11 | Temporal (Parenchymal) | Neg | Neg | 215 | 147 |
| 12 | Cerebellum (Parenchymal) | Neg | Neg | 98 | 57 |
| 13 | Sellar Region (Parenchymal) | Neg | Pos | 158 | 90 |
| 14 | T10–11 (Dural) | Pos | Neg | 209 | 157 |
| 15 | Frontotemporal (Dural) | Neg | Neg | 116 | 90 |
| 16 | T6–7 (Dural) | Neg | Pos | 207 | 95 |
| 17 | Frontoparietal (Dural) | Neg | Pos | 92 | 68 |
| 18 | T8–10 (Dural) | Neg | Neg | 98 | 24 |
| 19 | T8 (Dural) | Neg | N/A | 144 | 92 |
| 20 | T1–4 (Dural) | Neg | N/A | 159 | 136 |
| 21 | Not specified (Dural) | Neg | Neg | 190 | 210 |