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. 2020 Jan 1;11(5):1017–1026. doi: 10.7150/jca.37590

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HE and immunohistochemical staining of the tumor tissue. Tumors from the mice treated with PBS (Control), VG9-IL-24, or VG9-EGFP were harvested, formalin fixed and paraffin embedded. Sections were subjected to HE staining and immunohistochemistry for Ki-67 and IL-24. Pyknosis events were obviously appeared in VG9-IL-24 group and decreased positive Ki-67 were also observed in VG9-IL-24 group. Expression of IL-24 was observed in tumors treated with VG9-IL-24. Original magnification, ×400. Bar: 20 μm.