. 2020 Jan 1;11(5):1075–1081. doi: 10.7150/jca.35127

Table 1.

Summary of associated variants identified by the meta-analysis.

Position	Locus	SNP	Allele^a	NJMU(n=5408)			FLCCA(n=8537)			Meta-analysis					RegulomeDB Score^d
Position	Locus	SNP	Allele^a	EAF^b	BETA	P	EAF^b	BETA	P	EAF^b	BETA	P	P_FDR-BH	P_het^c	RegulomeDB Score^d
chr1:146731367	1q21.1	rs17160062	C/T	0.12	0.15	1.55E-02	0.12	0.18	7.95E-05	0.12	0.17	4.00E-06	8.63E-03	0.687	3a
chr2:25744731	2p23.3	rs670343	A/G	0.55	-0.17	3.87E-05	0.52	-0.10	1.26E-03	0.53	-0.13	4.87E-07	1.65E-03	0.156	3a
chr2:61763165	2p15	rs9309336	C/T	0.6	0.13	3.60E-03	0.61	0.12	2.74E-04	0.61	0.12	3.24E-06	7.69E-03	0.833	3a
chr6:117803538	6q22.1	rs4946258	T/C	0.45	-0.1	2.65E-02	0.44	-0.15	3.35E-06	0.45	-0.13	4.16E-07	1.65E-03	0.339	1b
chr17:40554849	17q21.2	rs9252	A/G	0.14	-0.21	1.74E-03	0.14	-0.14	1.98E-03	0.14	-0.16	1.51E-05	2.98E-02	0.424	2b

^a Effect allele/other allele.^b Effect allele frequency.^c P value for heterogeneity. ^d Regulome DB score is a kind of functional prediction scores that evaluate SNPs functionality based upon experimental data, such as its existence in a DNAaseI hypersensitive site or transcription factor binding site.