Table 2.
Univariate and multivariate analyses for overall survival in patients with NSCLC.
| Variables | univariate | multivariate | Variables | univariate | multivariate | Variables |
|---|---|---|---|---|---|---|
| HR | 95%CI | HR | 95%CI | |||
| Age,years (>65 vs ≤65) | 1.396 | 0.825-2.360 | 0.213 | - | - | - |
| Gender (male vs female) | 1.648 | 1.019-2.665 | 0.042 | 0.918 | 0.518-1.627 | 0.769 |
| Smoking (YES vs NO) | 0.946 | 0.594-1.507 | 0.816 | - | - | - |
| Histology(squamous vs non-squamous) | 2.015 | 1.148-3.56 | 0.015 | 1.189 | 0.565-2.502 | 0.648 |
| Pathological T (T3-4 vs T1-2) | 4.488 | 2.377-8.473 | <0.001 | 3.211 | 1.440-7.160 | 0.004 |
| Lymph node metastasis (N1-3vs N0) | 1.865 | 1.125-3.092 | 0.016 | 1.388 | 0.756-2.550 | 0.290 |
| Differentiation (poor VS well, moderate) | 1.107 | 0.669-1.833 | 0.693 | - | - | - |
| EGFR mutation status (NO vs YES) | 1.337 | 0.830-2.154 | 0.233 | - | - | - |
| Staging (III, IV vs I, II) | 7.104 | 3.705-13.622 | <0.001 | 5.168 | 2.353-11.352 | - |
| TF in plasma (high vs low) | 2.512 | 1.551-4.068 | <0.001 | 2.030 | 1.212-3.398 | 0.007 |