Table 5.

Conditional indirect effects of stress or compulsive eating on the effect of treatment randomization (mindfulness vs. active control) on change in study outcomes at multiple timepoints.

	Direct Effect of X on Y, B (SE)	95% CI of Direct Effect	P	Point Estimate of Indirect Effect, B (SE)	95% CI of Indirect Effect
Δ Weight, 12m
Mediator 1 (ME1): Δ DEBQ-EE, 6m	−1.69 (1.14)	(−3.94, 0.56)	.14	−0.35 (.30)	(−1.20, 0.04)
Mediator 2 (ME2): Δ BES, 6m	−1.64 (1.13)	(−3.87, 0.59)	.15	−0.37 (0.27)	(−1.07, 0.03)
Δ Weight, 18m
Mediator 1 (ME1): Δ DEBQ-EE, 6m	−1.53 (1.40)	(−4.30, 1.23)	.27	−0.24 (0.29)	(−1.11, 0.11)
Mediator 2 (ME2): Δ BES, 6m	−1.51 (1.40)	(−4.28, 1.26)	.28	−0.23 (0.26)	(−0.98, 0.09)
Δ FBG, 12m
Mediator 1 (ME1): Δ DEBQ-EE, 6m	−2.90 (1.50)	(−5.87, 0.08)	.06†	−0.28 (0.28)	(−1.15, 0.04)
Mediator 2 (ME2): Δ BES, 6m	−2.99 (1.52)	(−6.01, 0.02)	.05*	−0.22 (0.22)	(−0.92, 0.05)
Δ FBG, 18m
Mediator 1 (ME1): Δ DEBQ-EE, 6m	−3.78 (1.45)	(−6.64, −0.91)	.01**	−0.23 (0.27)	(−1.05, 0.11)
Mediator 2 (ME2): Δ BES, 6m	−3.61 (1.43)	(−6.43, −0.79)	.01**	−0.32 (0.34)	(−1.31, 0.11)

Note.

^*p ≤ .05,

^**p ≤ .01,

^†trend-level significance. All 95% Confidence Intervals (CIs) represent bootstrapped (5,000) and bias-corrected estimates (BCEs). SE=Standard Error. Effects are unstandardized coefficients from models testing each mediator (DEBQ-EE, BES) separately. X=mindfulness vs. control, Y=Δ each metabolic outcome at each timepoint, ME1= Δ stress eating at 6m; ME2 Δcompulsive eating at 6m.

See Table 1 note.