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. 2020 Jan 14;10:255. doi: 10.1038/s41598-019-57182-4

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Clustering dendrogram and module-trait correlation plots. The upper panel of each plot (A–D) represents metabolite-clustering dendrogram obtained by hierarchical clustering of TOM-based dissimilarity with the corresponding module colors indicated by the color row. Each colored row represents color-coded module that contains a group of highly connected metabolites. The lower panel of each plot (a–d) represents the module trait correlation where the x-axis represents feed efficiency trait, and the y-axis represents the modules. Plots (A) and (B) represents Duroc at time points one and two, respectively, while plots (C) and (D) represent Landrace at time points one and two. The color-coding in the module-trait correlation plots is based on Spearman’s correlation (p-values in parenthesis). Positive and negative correlations are shown in red and blue colors, respectively.