Table 1.
Patient Demographics and Comparison of Biomarker Levels (Page 1 of 2).
| COHORT A - TRAINING | Burn AKI | Burn Non-AKI | ||
|---|---|---|---|---|
| (n = 25) | (n = 25) | |||
| Mean (SD) Age (years) | 39.1 (49.2) | 39.7 (15.5) | ||
| Gender (M/F) | 20/5 | 19/6 | ||
| Burn Size (%TBSA) | 49.2 (24.1) | 43.3 (18.9) | ||
| Mean (SD) Arterial Pressure (mmHg) | 78.9 (11.5) | 80.1 (5.2) | ||
| Mean (SD) Central Venous Pressure (mmHg) | 13.3 (3.4) | 12.0 (7.6) | ||
| Mean (SD) Creatinine (mg/dL) | 1.21 (0.51) | 0.90 (0.22) | ||
| Mean (SD) NGAL (ng/mL) | 185.1 (86.3) | 110.3 (48.1) | ||
| Mean (SD) NT-proBNP (pg/mL) | 25.7 (15.4) | 16.0 (15.3) | ||
| Mean (SD) UOP (mL/hr) | 81.5 (31.6) | 85.7 (48.9) | ||
| Mean (SD) Time to AKI (hours)a | 42.7 (23.2) | N/A | ||
| COHORT B - TEST | Burn AKI | Burn Non-AKI | Trauma AKI | Trauma Non-AKI |
| (n = 6) | (n = 15) | (n = 7) | (n = 23) | |
| Mean (SD) Age (years) | 38.2 (41.5) | 40.1 (20.2) | 37.6 (39.9) | 39.1 (19.5) |
| Gender (M/F) | 4/2 | 12/3 | 4/3 | 15/10 |
| Burn Size (%TBSA) | 41.1 (14.8) | 40.0 (20.4) | N/A | N/A |
| Mean (SD) Arterial Pressure (mmHg) | 82.8 (15.5) | 79.7 (18.3) | 70.3 (20.8) | 75.1 (20.3) |
| Mean (SD) Central Venous Pressure (mmHg) | 12.6 (4.4) | 12.9 (5.8) | 10.7 (6.2) | 12.3 (6.9) |
| Mean (SD) Creatinine (mg/dL) | 2.15 (1.77) | 0.93 (0.46) | 2.16 (1.57) | 0.86 (0.32) |
| Mean (SD) NGAL (ng/mL) | 300.4 (213.5) | 110.0 (39.7) | 396.7 (393.7) | 77.4 (32.1) |
| Mean (SD) NT-proBNP (pg/mL) | 144.3 (23.6) | 57.5 (16.9) | 137.3 (62.1) | 93.7 (10.4) |
| Mean (SD) UOP (mL/hr) | 47.7 (41.2) | 93.3 (41.1) | 66.1 (37.2) | 87.4 (58.2) |
| Mean (SD) Time to AKI (hours)a | 43.9 (15.3) | N/A | 82.7 (38.6) | N/A |
Note: aTime from admission to achieving AKI based on KDIGO criteria.
Abbreviations: F, female; KDIGO, Kidney Disease: Improving Global Outcomes; M, male; mmHg, millimeters mercury; mL, milliliter; ng, nanogram; NGAL, neutrophil gelatinase associated lipocalin; N/A, not applicable; NT-proBNP; N-terminal pro-B-type natriuretic peptide; pg, picogram; SD, standard deviation; TBSA, total body surface area; and UOP, urine output.