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. Author manuscript; available in PMC: 2020 Jan 14.
Published in final edited form as: DNA Repair (Amst). 2019 Mar 7;77:76–86. doi: 10.1016/j.dnarep.2019.03.004

Fig. 2. Mammalian pol ζ protects against AFB1-induced cytotoxicity.

Fig. 2.

(A) Growth inhibition in Rev3L+/− (circles), Rev3L−/− (squares), and Rev3L−/− +hRev3L (triangles) MEFs was determined 48 h after AFB1 treatment by measuring cellular ATP. (B) Quantification of total cell death (Annexin V+/PI-, Annexin V-/PI + and Annexin V+/PI+) in Rev3L+/− (black bars) and Rev3L−/− (gray bars) MEFs following AFB1 treatment. Data represent mean ± SEM from three independent experiments. * P < 0.05 by unpaired two-tailed t-test with unequal variances. [Reproduced from [57], Fig. 1, Panels A and B].