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. 2019 Nov 3;9(1):1683347. doi: 10.1080/2162402X.2019.1683347

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© 2019 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Prognostic associations of TIL subpopulations in AML. (a) Forest plots showing the associations of continuous TIL concentrations with overall survival (OS, left) and event-free survival (EFS, right) in Cohort 2. The hazard ratios (HRs) were plotted with lower and upper 95% confidence intervals (CI) in the forest plots. p-values were obtained from a univariate Cox regression analysis. (b) OS and EFS in AML patients (Cohort 2) defined by quartiles (Q1-Q4) of M2 macrophage abundances. The relative abundances of M2 macrophages were estimated by CIBERSORT (left panel) and xCell (right panel), respectively. Depicted p-values were calculated from log-rank tests.