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. 2019 Nov 3;9(1):1684126. doi: 10.1080/2162402X.2019.1684126

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© 2019 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Different expression patterns of receptors on TILs and on PBMCs.

The percentage of (a) NK cells, (b) CD4+ T cells and (c) CD8+ T cells among all lymphocytes in tumorbiopsies obtained during perfusion and in peripheral blood taken before ILP. Expression of (d-f)CXCR3, (g-i) CCR4, (j-l) CCR5 and (m-o) PD-1 on (d,g,j,m) NK cells, (e,h,k,n) CD4+ T cellsand (f,i,l,o) CD8+ T cells in tumors (TILs) and in peripheral blood (PBMCs) (n=8; paired Wilcoxon test). MFI = Median Fluorescence Intensity. Data are presented in box-and-whiskers plots with min. and max.