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Melphalan-exposed melanoma cells induce expression of CXCL10, CCL2 and IFN-γ in PBMCs during co-culture.
PBMCs from healthy donors were cultured with melphalan-exposed melanoma cells, non-exposed melanoma cells or were cultured alone for 48 h. After 48 h the levels of (a) CXCL10, (b) CCL2 and (c) IFN-γ were measured in the cell culture supernatants (n = 9; paired Friedman test followed by Dunn’s multiple comparison test). Data are presented as mean with SEM.
