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. 2019 Nov 24;9(1):1682381. doi: 10.1080/2162402X.2019.1682381

Figure 3.

Figure 3.

ADP-A2M4 display alloreactivity toward HLA-A*02:05. (a) ADP-A2M4 respond to two HLA-A*02:05 EBV-derived B-LCLs (FH25, FH41; blue points) but not other cell lines. (b) ADP-A2M4 react to 2/3 HLA-A*02:05-expressing human primary cells. (c) ADP-A2M4 respond to human primary Schwann cells transduced to express HLA-A*02:05 but not other HLA-A2 alleles. Points in all panels show IFNγ release from ADP-A2M4 (red or blue points) and non-transduced cells (gray points), as determined by cell-ELISA. Each point reflects the average response of a single T-cell product in multiple independent experiments (three T cell products tested).