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. 2019 Dec 17;56(2):439–447. doi: 10.3892/ijo.2019.4945

Figure 5.

Figure 5

OPD' regulates FasL, androgen receptor and prostate-specific antigen through RIPK1. (A) Western blotting was used to detect the effects of OPD' on target proteins FasL, Fas and Bim in LNCaP cells. (B) Western blotting was used to detect the effects of OPD' on the protein expression of FasL following treatment with Nec-1 and/or OPD'. (C) Western blotting was used to detect the effects of OPD' on target proteins AR and PSA in LNCaP cells. (D) Western blotting was used to detect the effects of OPD' on the protein expression of AR and PSA following treatment with Nec-1 and/or OPD'. OPD', Ophiopogonin D'; FasL, Fas ligand; Nec-1, necrostatin-1; Bim, Bcl-2-like protein 11; AR, androgen receptor; PSA, prostate-specific antigen.