Table 1.
Correlations of EphB3 and Dysadherin Protein Expression with the Clinicopathological Characteristics of ECC
| CPC | Number of Patients(n) | EphB3 | Dysadherin | ||||
|---|---|---|---|---|---|---|---|
| Pos No. (%) | χ2 | P | Pos No. (%) | χ2 | P | ||
| Age (year) | |||||||
| ≤45 years | 17 | 10 (58.8) | 2.380 | 0.123 | 7 (41.2) | 1.581 | 0.209 |
| >45 years | 83 | 32 (38.6) | 48 (57.8) | ||||
| Gender | |||||||
| Male | 61 | 24 (39.3) | 0.453 | 0.501 | 34(55.7) | 0.034 | 0.853 |
| Female | 39 | 18 (46.2) | 21 (53.8) | ||||
| Differentiation | |||||||
| Well | 31 | 21 (67.7) | 17.373 | 0.000 | 9(29.0) | 15.390 | 0.000 |
| Moderately | 34 | 15 (44.1) | 19 (55.9) | ||||
| Poorly | 35 | 6 (17.1) | 27 (77.1) | ||||
| Tumor size | |||||||
| ≤3cm | 62 | 27 (43.5) | 0.161 | 0.689 | 33 (53.2) | 0.208 | 0.649 |
| >3cm | 38 | 15 (39.5) | 22 (57.9) | ||||
| Tumor location | |||||||
| Hilar site | 27 | 9 (33.3) | 1.850 | 0.397 | 21 (77.8) | 9.135 | 0.010 |
| Hepatic duct | 4 | 1 (25.0) | 3 (75.0) | ||||
| Distal duct | 69 | 32 (46.4) | 31 (44.9) | ||||
| Bile stone | |||||||
| Absent | 69 | 31 (44.9) | 0.783 | 0.376 | 36 (52.2) | 0.718 | 0.397 |
| Present | 31 | 11 (35.5) | 19 (61.3) | ||||
| Lymph node metastasis | |||||||
| Negative | 62 | 37 (59.7) | 20.930 | 0.000 | 24 (38.7) | 17.494 | 0.000 |
| Positive | 38 | 5 (13.2) | 31 (81.6) | ||||
| Invasion | |||||||
| Negative | 33 | 21 (63.6) | 9.465 | 0.002 | 9 (27.3) | 15.300 | 0.000 |
| Positive | 67 | 21 (31.3) | 46 (68.7) | ||||
| TNM stage | |||||||
| I + II | 35 | 23 (65.7) | 21.460 | 0.000 | 8 (22.9) | 27.608 | 0.000 |
| III | 38 | 17 (44.7) | 23 (60.5) | ||||
| IV | 27 | 2 (7.4) | 24 (88.9) | ||||
| Surgery | |||||||
| Radical | 54 | 32 (59.3) | 14.371 | 0.001 | 20 (37.0) | 15.383 | 0.000 |
| Palliative | 36 | 8 (22.2) | 27 (75.0) | ||||
| Biopsy | 10 | 2 (20.0) | 8 (80.0) | ||||
Abbreviations: CPC, Clinicopathological characteristics; Pos No., Positive Number.