Table 4.
Correlations of Clinicopathological Characteristics, EphB3 and Dysadherin Expression with the Mean Survival in Patients with ECC
| Group | Number of Patients (n) | Median Survival (Month) | Log-Rank χ2 | P |
|---|---|---|---|---|
| Sex | ||||
| Male | 61 | 12.67 (3–30) | 0.001 | 0.980 |
| Female | 39 | 12.59 (4–30) | ||
| Age (year) | ||||
| ≤45 | 17 | 13.82 (3–30) | 0.667 | 0.414 |
| >45 | 83 | 12.10 (3–30) | ||
| Differentiation | ||||
| Well | 31 | 18.46 (5–30) | 27.655 | 0.000 |
| Moderately | 34 | 11.41 (3–30) | ||
| Poorly | 35 | 7.97 (3–30) | ||
| Tumor size | ||||
| ≤3cm | 62 | 12.62 (3–30) | 0.235 | 0.628 |
| >3cm | 38 | 12.03 (5–30) | ||
| TNM stage | ||||
| I + II | 35 | 18.57 (7–30) | ||
| III | 38 | 11.05 (3–30) | 57.569 | 0.000 |
| IV | 27 | 6.26 (3–13) | ||
| Lymph node metastasis | ||||
| No | 62 | 15.52 (4–30) | 39.001 | 0.000 |
| Yes | 38 | 7.18 (3–25) | ||
| Invasion | ||||
| No | 33 | 17.52 (4–30) | 17.399 | 0.000 |
| Yes | 67 | 9.87 (3–30) | ||
| Surgery | ||||
| Radical | 54 | 16.62 (3–30) | 48.388 | 0.000 |
| Palliative | 36 | 7.58 (4–24) | ||
| Biopsy | 10 | 6.90 (3–14) | ||
| EphB3 | ||||
| − | 58 | 8.35 (3–25) | 37.806 | 0.000 |
| + | 42 | 17.88 (7–30) | ||
| Dysadherin | ||||
| − | 45 | 17.11 (5–30) | 32.224 | 0.000 |
| + | 55 | 8.46 (3–25) | ||
| EphB3 and Dysadherin | ||||
| EphB3(−) and Dysadherin (−) | 13 | 10.92(5–20) | 48.278 | 0.000 |
| EphB3(+) and Dysadherin (−) | 32 | 19.63(7–30) | ||
| EphB3(−) and Dysadherin (+) | 45 | 7.60(3–25) | ||
| EphB3(+) and Dysadherin (+) | 10 | 12.30(7–24) |
Abbreviations: −, negative expression; +, positive expression.