Table 3.
Summary of CO-FISH experiments where we substituted the growth medium with dCTP, in order to allevialte BrdU’s cytotoxic effects
| WW:CC | WC:WC | REC | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ok | 1inc. | 2 inc. | 1doub. | 1inc, ldoub. | 2doub. | High confidence | Reduced confidence | ok | 1inc. | 2inc. | 1doub. | 1inc.1doub. | 2doub. | High confidence | Reduced confidence | % of total | ||
| Chr. 7 (2.5/400) | 4 | 0 | 5 | 1 | 0 | 0 | 9 | 1 | 2 | 3 | 1 | 0 | 0 | 3 | 6 | 3 | 4 | 17.4 |
| Chr. 7 (1.25/200) | 5 | 13 | 8 | 1 | 3 | 5 | 26 | 9 | 5 | 8 | 4 | 2 | 5 | 1 | 17 | 8 | 15 | |
| Chr. 11 (1.25/200) | 2 | 10 | 7 | 2 | 2 | 1 | 19 | 5 | 4 | 4 | 4 | 1 | 3 | 1 | 12 | 5 | 5 | 16.5 |
We still detect random segregation for chromosomes 7 and 11. Metaphases were subdivided into seven classes as in Table 1